Response to comment on “Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2”

Authors: Michael D. Nicholson, Lukas Endler, Alexandra Popa, Jakob-Wendelin Genger, Christoph Bock, Franziska Michor, Andreas Bergthaler

Published: 2021-10-27

DOI: 10.1126/scitranslmed.abj3222

Source: Full article

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Abstract

Further analysis of SARS-CoV-2 genome sequencing data identifies several highly recurrent genetic variants with low allele frequencies, which, if filtered out, provide estimates consistent with tighter transmission bottlenecks.