Pre–T cell receptors topologically sample self-ligands during thymocyte β-selection

Authors: Xiaolong Li, Réka Mizsei, Kemin Tan, Robert J. Mallis, Jonathan S. Duke-Cohan, Aoi Akitsu, Paul W. Tetteh, Abhinav Dubey, Wonmuk Hwang, Gerhard Wagner, Matthew J. Lang, Haribabu Arthanari, Jia-huai Wang, Ellis L. Reinherz

Published: 2021-01-07

DOI: 10.1126/science.abe0918

Source: Full article

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Abstract

PreTCRs use horizontal docking geometry