Noncanonical crRNAs derived from host transcripts enable multiplexable RNA detection by Cas9

Authors: Chunlei Jiao, Sahil Sharma, Gaurav Dugar, Natalia L. Peeck, Thorsten Bischler, Franziska Wimmer, Yanying Yu, Lars Barquist, Christoph Schoen, Oliver Kurzai, Cynthia M. Sharma, Chase L. Beisel

Published: 2021-04-27

DOI: 10.1126/science.abe7106

Source: Full article

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Abstract

Cellular RNAs guide CRISPR-Cas9