Inhaled siRNA nanoparticles targeting

Authors: Xin Bai, Guolin Zhao, Qijing Chen, Zhongyu Li, Mingzhu Gao, William Ho, Xiaoyang Xu, Xue-Qing Zhang

Published: 2022-06-22

DOI: 10.1126/sciadv.abn7162

Source: Full article


Abstract

Interleukin-11 (IL-11) is a profibrotic cytokine essential for the differentiation of fibroblasts into collagen-secreting, actin alpha 2, smooth muscle–positive (ACTA2