Authors: Seung Min Lee, Jin Woo Lee, Inki Kim, Dong-Cheol Woo, Chan-Gi Pack, Young Hoon Sung, In-Jeoung Baek, Chang Hee Jung, Young-Hak Kim, Chang Hoon Ha
Published: 2022-12-02
Source: Full article
C1q/tumor necrosis factor–related protein 9 (CTRP9) is an adipokine and has high potential as a therapeutic target. However, the role of CTRP9 in cardiovascular disease pathogenesis remains unclear. We found CTRP9 to induce HDAC7 and p38 MAPK phosphorylation via tight regulation of AMPK in vascular endothelial cells, leading to angiogenesis through increased