Authors: Youichi Shinozaki, Alex Leung, Kazuhiko Namekata, Sei Saitoh, Huy Bang Nguyen, Akiko Takeda, Yosuke Danjo, Yosuke M. Morizawa, Eiji Shigetomi, Fumikazu Sano, Nozomu Yoshioka, Hirohide Takebayashi, Nobuhiko Ohno, Takahiro Segawa, Kunio Miyake, Kenji Kashiwagi, Takayuki Harada, Shin-ichi Ohnuma, Schuichi Koizumi
Published: 2022-11-04
Source: Full article
Astrocyte abnormalities have received great attention for their association with various diseases in the brain but not so much in the eye. Recent independent genome-wide association studies of glaucoma, optic neuropathy characterized by retinal ganglion cell (RGC) degeneration, and vision loss found that single-nucleotide polymorphisms near the ABCA1 locus were common risk factors. Here, we show that