Reduced insulin signaling in neurons induces sex-specific health benefits

Authors: Maarouf Baghdadi, Tobias Nespital, Andrea Mesaros, Sandra Buschbaum, Dominic J. Withers, Sebastian Grönke, Linda Partridge

Published: 2023-02-22

DOI: 10.1126/sciadv.ade8137

Source: Full article

---

Abstract

Reduced activity of insulin/insulin-like growth factor signaling (IIS) extends health and life span in mammals. Loss of the