The causal mutation leading to sweetness in modern white lupin cultivars

Authors: Davide Mancinotti, Katarzyna Czepiel, Jemma L. Taylor, Hajar Golshadi Galehshahi, Lillian A. Møller, Mikkel K. Jensen, Mohammed Saddik Motawia, Bárbara Hufnagel, Alexandre Soriano, Likawent Yeheyis, Louise Kjaerulff, Benjamin Péret, Dan Staerk, Toni Wendt, Matthew N. Nelson, Magdalena Kroc, Fernando Geu-Flores

Published: 2023-08-04

DOI: 10.1126/sciadv.adg8866

Source: Full article


Abstract

Lupins are high-protein crops that are rapidly gaining interest as hardy alternatives to soybean; however, they accumulate antinutritional alkaloids of the quinolizidine type (QAs). Lupin domestication was enabled by the discovery of genetic loci conferring low QA levels (sweetness), but the precise identity of the underlying genes remains uncertain. We show that