Chromatin analysis of adult pluripotent stem cells reveals a unique stemness maintenance strategy

Authors: Axel Poulet, Arcadia J. Kratkiewicz, Danyan Li, Josien C. van Wolfswinkel

Published: 2023-10-06

DOI: 10.1126/sciadv.adh4887

Source: Full article


Abstract

Many highly regenerative organisms maintain adult pluripotent stem cells throughout their life, but how the long-term maintenance of pluripotency is accomplished is unclear. To decipher the regulatory logic of adult pluripotent stem cells, we analyzed the chromatin organization of stem cell genes in the planarian