Structural basis for subversion of host cell actin cytoskeleton during

Authors: Biao Yuan, Jonas Scholz, Jiri Wald, Roland Thuenauer, Rory Hennell James, Irina Ellenberg, Sabine Windhorst, Jan Faix, Thomas C. Marlovits

Published: 2023-12-08

DOI: 10.1126/sciadv.adj5777

Source: Full article

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Abstract

Secreted bacterial type III secretion system (T3SS) proteins are essential for successful infection by many human pathogens. Both T3SS translocator SipC and effector SipA are critical for