Checkmate: Metabolic flexibility with a STING in its tail

Authors: Roddy S. O’Connor

Published: 2023-12-06

DOI: 10.1126/sciadv.adm6816

Source: Full article

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Abstract

Inhibiting a key metabolic enzyme, ACLY, in cancer cells impacts T cell function in immunotherapy-resistant tumors and may offer a target for therapeutic treatment.