A human obesity-associated MC4R mutation with defective Gq/11α signaling leads to hyperphagia in mice

Authors: Peter J. Metzger, Aileen Zhang, Bradley A. Carlson, Hui Sun, Zhenzhong Cui, Yongqi Li, Marshal T. Jahnke, Daniel R. Layton, Meenakshi B. Gupta, Naili Liu, Evi Kostenis, Oksana Gavrilova, Min Chen, Lee S. Weinstein

Published: 2024-01-04

DOI: 10.1172/jci165418

Source: Full article

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Abstract

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