Genetic deletion or pharmacologic inhibition of histone deacetylase 6 protects the heart against ischaemia/reperfusion injury by limiting tumour necrosis factor alpha–induced mitochondrial injury in experimental diabetes

Authors: Shelley L Baumgardt, Juan Fang, Xuebin Fu, Yanan Liu, Zhengyuan Xia, Ming Zhao, Ling Chen, Rachana Mishra, Muthukumar Gunasekaran, Progyaparamita Saha, Joseph M Forbess, Zeljko J Bosnjak, Amadou K S Camara, Judy R Kersten, Edward B Thorp, Sunjay Kaushal, Zhi-Dong Ge

Published: 2024-07-13

DOI: 10.1093/cvr/cvae144

Source: Full article

Genetic deletion or pharmacologic inhibition of histone deacetylase 6 protects the heart against ischaemia/reperfusion injury by limiting tumour necrosis factor alpha–induced mitochondrial injury in experimental diabetes

Abstract