IL-13Rα2/TGF-<b>β</b> bispecific CAR-T cells counter TGF-<b>β</b>-mediated immune suppression and potentiate anti-tumor responses in glioblastoma

Authors: Andrew J Hou, Ryan M Shih, Benjamin R Uy, Amanda Shafer, ZeNan L Chang, Begonya Comin-Anduix, Miriam Guemes, Zoran Galic, Su Phyu, Hideho Okada, Katie B Grausam, Joshua J Breunig, Christine E Brown, David A Nathanson, Robert M Prins, Yvonne Y Chen

Published: 2024-07-08

DOI: 10.1093/neuonc/noae126

Source: Full article

IL-13Rα2/TGF-<b>β</b> bispecific CAR-T cells counter TGF-<b>β</b>-mediated immune suppression and potentiate anti-tumor responses in glioblastoma

Abstract