Authors: Elina Fredlund, Stina Andersson, Elien Hilgert, Ezequiel Monferrer, Guadalupe Álvarez-Hernán, Sinan Karakaya, Siebe Loontiens, Jan Willem Bek, Tomas Gregor, Estelle Lecomte, Emma Magnusson, Enrika Miltenyte, Marie Cabirol, Michail Kyknas, Niklas Engström, Marie Arsenian Henriksson, Emma Hammarlund, Jared S. Rosenblum, Rosa Noguera, Frank Speleman, Johan van Nes, Sofie Mohlin
Published: 2024-06-21
Source: Full article
Neuroblastoma is a childhood developmental cancer; however, its embryonic origins remain poorly understood. Moreover, in-depth studies of early tumor-driving events are limited because of the lack of appropriate models. Herein, we analyzed RNA sequencing data obtained from human neuroblastoma samples and found that loss of expression of trunk neural crest–enriched gene