Authors: Liping Wang, Penghao Ji, Jiadie Yu, Shuwen Qiu, Bolin An, Minfeng Huo, Jianlin Shi
Published: 2024-10-30
Source: Full article
Living therapeutics is an emerging antitumor modality by living microorganisms capable of selective tropism and effective therapeutics. Nevertheless, primitive microbes could only present limited therapeutic functionalities against tumors. Hybridization of the microbes with multifunctional nanocatalysts is of great significance to achieve enhanced tumor catalytic therapy. In the present work, nitric oxide synthase (NOS)–engineered