FTO regulates ELK3-mediated metabolic rewiring and represents a unique therapeutic target in T cell leukemia

Authors: Hao Huang, Xinlu Li, Jinlian Luo, Chuan Gao, Mengjie Yang, Jin Xu, Ting Xie, Zhi Chen, Donghai Wang, Yuan Wang, Hua-Bing Li, Jinyan Huang, Yu Liu, Haojian Zhang, Panagiotis Ntziachristos, Yun Zhao, Guoliang Qing, Hudan Liu

Published: 2025-05-28

DOI: 10.1126/sciadv.adq3052

Source: Full article

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Abstract

Understanding the regulation of N6-methyladenosine (m