Authors: Ying He, Xiaoya Tang, Hao Fu, Yihang Tang, Honghui Lin, Xingguang Deng
Published: 2025-02-05
Source: Full article
Proper chromosome segregation during cell division is essential for genomic integrity and organismal development. This process is monitored by the spindle assembly checkpoint (SAC), which delays anaphase onset until all chromosomes are properly attached to the mitotic spindle. The kinetochore protein KNL1 plays a critical role in recruiting SAC proteins. Here, we reveal that