Its own architect: Flipping cardiolipin synthase

Authors: Katsuhiro Sawasato, William Dowhan, Mikhail Bogdanov

Published: 2025-01-03

DOI: 10.1126/sciadv.ads0244

Source: Full article

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Abstract

Current dogma assumes that lipid asymmetry in biological membranes is actively maintained and dispensable for cell viability. The inner (cytoplasmic) membrane (IM) of