A multimodal defect-rich nanoreactor triggers sono-piezoelectric tandem catalysis and iron metabolism disruption for implant infections

Authors: Fuyuan Zheng, Xufeng Wan, Yangming Zhang, Yan Yue, Qiaochu Li, Zhuang Zhang, Shuoyuan Li, Hong Xu, Qiang Su, Xiaoting Chen, Le Tong, Long Zhao, Jian Cao, Xin Tang, Xiao Yang, Jiagang Wu, Jian Li, Xiang Lv, Zongke Zhou, Duan Wang

Published: 2025-03-14

DOI: 10.1126/sciadv.ads8694

Source: Full article

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Abstract

Tracking and eradicating drug-resistant bacteria are critical for combating implant-associated infections, yet effective antibacterial therapies remain elusive. Herein, we propose an oxygen vacancy–rich (BiFe)