Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis

Authors: Tantan Long, Yumei Lu, Yuanyuan Ma, Yandong Song, Xiaoping Yi, Xiaomei Chen, Miaomiao Zhou, Jingyi Ma, Jiayuan Chen, Zhuoliang Liu, Fengxin Zhu, Zheng Hu, Zhanmei Zhou, Chaoyang Li, Fan Fan Hou, Lirong Zhang, Yupeng Chen, Jing Nie

Published: 2025-04-16

DOI: 10.1126/scitranslmed.adj9095

Source: Full article

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Abstract

Cellular prion protein (PrP