Co-inhibition of Notch1 and ChK1 triggers genomic instability and melanoma cell death increasing the lifespan of mice bearing melanoma brain metastasis

Authors: Varsha Thakur, Vijay S. Thakur, Dazhi Wang, Juliano Tiburcio de Freitas, Anna Bianchi, Luis Alberto Nivelo, Oliver Umland, Scott M. Welford, Barbara Bedogni

Published: 2025-05-28

DOI: 10.1186/s13046-025-03411-w

Source: Full article


Abstract

Abstract