Biosynthetic gene clusters and the evolution of fungal chemodiversity

Authors: Antonis Rokas, Matthew E. Mead, Jacob L. Steenwyk, Huzefa A. Raja, Nicholas H. Oberlies

Published: 2020-01-03

DOI: 10.1039/c9np00045c

Source: Full article

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Abstract

This highlight synthesizes knowledge of the molecular evolutionary processes – functional divergence, horizontal transfer, andde novoassembly – that govern biosynthetic gene cluster diversification and the generation of chemodiversity in fungi.