Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine

Authors: K. C. Nicolaou, Stephan Rigol

Published: 2020-04-22

DOI: 10.1039/d0np00003e

Source: Full article

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Abstract

This review article summarises a series of total syntheses of natural and designed molecules primarily for biology and medicine. Aspects of new synthetic strategies and methods and optimisation of biological properties are emphasised.