Authors: Maria Carolina Cabral de Lacerda, Leonardo Ferreira Caixeta
Published: 2020-12-07
DOI: 10.1002/alz.044030
Source: Full article
AbstractBackgroundIn the twentieth century, it was believed that the injury cortical was the substrate of cerebral dysfunction neuropathological. Studies of dementia were primarily focused on disorders of the cerebral cortex and sub cortical gray region, which originated the concepts of cortical and subcortical dementia respectively. The report of dementia mainly involving the white brain received less attention.Method15 patients were evaluated with DSB, 8 with DSC and 14 control subjects. We applied the following tests: Boston for Diagnostic of Aphasia Examination (BDAE), the Boston Naming Test (BNT), Token Test, Verbal fluency ‐ semantic category and board Theft of biscuits.ResultThe results showed that the subcortical group showed worse performance with the control group, showing significant differences in the Boston Naming Test and on the evidence of comprehension and oral production and graphics for the Boston Diagnostic Test of Aphasia. The DSB group showed more significant changes when compared with the control group than in the comparison between DSC X control group. Despite the language is related to cortical involvement, our study showed that such changes are found in subcortical dementia and receiving influence of cognitive processes involved in language. Symptoms of changes in language were similar between groups subcortical, but in greater or lesser degree of commitment. The DSB group showed more impairment of comprehension and oral apraxia and DSC group is highlighted by changes in prosody and the presence of hyperkinetic dysarthria.ConclusionThe subcortical groups showed greater language impairment than the control group, formed by patients with cortical dementia and the domains most seriously involved were those of complex ideational understanding, oral and graphic speech, naming and apraxia, also another symptom present exclusively in this group.